That's interesting. So far, more than one of the anti-malaria drugs I've read about (on #Wikipedia ... I'm not at the level yet where I could read a study abstract and come away with any kind of high-level overview or feeling of understanding) have a statement to the effect "we don't really know how or why this works".
Tonight's reading was https://en.wikipedia.org/wiki/Artemisinin (derived from a kind Artemisia [wormwood]).